Inhibition of HeLa cell growth by doxorubicin-loaded and tuftsin-conjugated arginate-PEG microparticles

Inhibition of HeLa cell growth by doxorubicin-loaded and tuftsin-conjugated arginate-PEG microparticles

In order to improve the release pattern of chemotherapy drug and reduce the possibility of drug resistance, poly(ethylene glycol amine) (PEG)-modified alginate microparticles (ALG-PEG MPs) were developed then two different mechanisms were employed to load doxorubicin (Dox): 1) forming Dox/ALG-PEG co...

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Bibliographic Details
Main Authors: Tianmu Hu, Anwar Saeed Ahmed Qahtan, Lei Lei, MD, PhD, Zhixin Lei, Dapeng Zhao, Hemin Nie, PhD
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2018-03-01
Series:Bioactive Materials
Subjects:
Controlled release
Tuftsin
Cellular uptake
Chemotherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X17300221

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http://www.sciencedirect.com/science/article/pii/S2452199X17300221

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