Umbilical-Cord-Derived Mesenchymal Stromal Cells Modulate 26 Out of 41 T Cell Subsets from Systemic Sclerosis Patients

Umbilical-Cord-Derived Mesenchymal Stromal Cells Modulate 26 Out of 41 T Cell Subsets from Systemic Sclerosis Patients

Systemic sclerosis (SSc) is an immune-mediated disease wherein T cells are particularly implicated, presenting a poor prognosis and limited therapeutic options. Thus, mesenchymal-stem/stromal-cell (MSC)-based therapies can be of great benefit to SSc patients given their immunomodulatory, anti-fibrot...

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Bibliographic Details
Main Authors: Paula Laranjeira, Francisco dos Santos, Maria João Salvador, Irina N. Simões, Carla M. P. Cardoso, Bárbara M. Silva, Helena Henriques-Antunes, Luísa Corte-Real, Sofia Couceiro, Filipa Monteiro, Carolina Santos, Tânia Santiago, José A. P. da Silva, Artur Paiva
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Biomedicines
Subjects:
mesenchymal stromal cells (MSCs)
mesenchymal stem cells
immunomodulatory potential
systemic sclerosis
T cells
T cell polarization
Online Access:https://www.mdpi.com/2227-9059/11/5/1329

Internet

https://www.mdpi.com/2227-9059/11/5/1329

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