Hydroxytyrosol mitigates Mycoplasma gallisepticum-induced pulmonary injury through downregulation of the NF-κB/NLRP3/IL-1β signaling pathway in chicken

Hydroxytyrosol mitigates Mycoplasma gallisepticum-induced pulmonary injury through downregulation of the NF-κB/NLRP3/IL-1β signaling pathway in chicken

ABSTRACT: In this study, the anti-inflammatory and antiapoptotic effects of hydroxytyrosol (HT) in Mycoplasma gallisepticum (MG)-infected chicken were investigated, and the underlying molecular mechanisms were explored. The results revealed severe ultrastructural pathological changes after MG infect...

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Bibliographic Details
Main Authors: Chunlan Shan, Yanling Xiong, Fujun Miao, Ting Liu, Rana Waseem Akhtar, Syed Aftab Hussain Shah, Hong Gao, Erpeng Zhu, Zhentao Cheng
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Poultry Science
Subjects:
hydroxytyrosol
Mycoplasma gallisepticum
chicken lung
inflammation
NF-κB/NLRP3/IL-1β signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S0032579123001062

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http://www.sciencedirect.com/science/article/pii/S0032579123001062

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