Design principles in mechanically adaptable biomaterials for repairing annulus fibrosus rupture: A review

Design principles in mechanically adaptable biomaterials for repairing annulus fibrosus rupture: A review

Annulus fibrosus (AF) plays a crucial role in the biomechanical loading of intervertebral disc (IVD). AF is difficult to self-heal when the annulus tears develop, because AF has a unique intricate structure and biologic milieu in vivo. Tissue engineering is promising for repairing AF rupture, but co...

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Bibliographic Details
Main Authors: Dan Zhou, Hongmei Liu, Zhaomin Zheng, Decheng Wu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-01-01
Series:Bioactive Materials
Subjects:
Annulus fibrosus
Forces
Mechanical matching
High tough
High adhesion
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X23002517

Internet

http://www.sciencedirect.com/science/article/pii/S2452199X23002517

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