NTRK3 REARRANGEMENT IN A NON-ROBERTSONIAN T(15;21)(Q25.3;Q22.1) IN AN PEDIATRIC PATIENT WITH PROGENITOR B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA WITH THE IAMP21
Objectives: Intrachromosomal amplification of chromosome 21 (iAMP21) occurs in 2% of B-cell acute lymphoblastic leukemia (ALL) and is considered to confer a poor prognosis. Alterations related to chromosome 21, such as the constitutional r(21)c and rob(15;21)c, have been associated with a high hazar...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-10-01
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| Series: | Hematology, Transfusion and Cell Therapy |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2531137921006465 |