Tunable hybrid hydrogels with multicellular spheroids for modeling desmoplastic pancreatic cancer

Tunable hybrid hydrogels with multicellular spheroids for modeling desmoplastic pancreatic cancer

The tumor microenvironment consists of diverse, complex etiological factors. The matrix component of pancreatic ductal adenocarcinoma (PDAC) plays an important role not only in physical properties such as tissue rigidity but also in cancer progression and therapeutic responsiveness. Although signifi...

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Bibliographic Details
Main Authors: Menekse Ermis, Natashya Falcone, Natan Roberto de Barros, Marvin Mecwan, Reihaneh Haghniaz, Auveen Choroomi, Mahsa Monirizad, Yeji Lee, Jihyeon Song, Hyun-Jong Cho, Yangzhi Zhu, Heemin Kang, Mehmet R. Dokmeci, Ali Khademhosseini, Junmin Lee, Han-Jun Kim
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-07-01
Series:Bioactive Materials
Subjects:
Pancreatic cancer
Desmoplasia
Fibrosis
Extracellular matrix
Tumor microenvironment
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X23000439

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http://www.sciencedirect.com/science/article/pii/S2452199X23000439

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