PTP1B Inhibitors from the Entomogenous Fungi Isaria fumosorosea

Protein tyrosine phosphatase 1B (PTP1B) is implicated as a negative regulator of insulin receptor (IR) signaling and a potential drug target for the treatment of type II diabetes and other associated metabolic syndromes. Thus, small molecule inhibitors of PTP1B can be considered as an attractive app...

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Bibliographic Details
Main Authors: Jun Zhang, Lin-Lin Meng, Jing-Jing Wei, Peng Fan, Sha-Sha Liu, Wei-Yu Yuan, You-Xing Zhao, Du-Qiang Luo
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/22/12/2058