Synthesis of a spin-labeled phospholipid for studying membrane dynamics in intact mammalian cells.
We report here the synthesis of a spin-labeled phospholipid, 1-palmitoyl-2-(4-doxylpentanoyl)glycerophosphocholine. The synthetic route for this probe involves two major steps: 1) the synthesis of 4-doxylpentanoic acid from ethyl levulinate and 2-amino-2-methyl propanol, and 2) the synthesis of the...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
1988-08-01
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| Series: | Journal of Lipid Research |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520384625 |