Collective total synthesis of stereoisomeric yohimbine alkaloids

Abstract Stereoisomeric polycyclic natural products are important for drug discovery-based screening campaigns, due to the close correlation of stereochemistry with diversified bioactivities. Nature generates the stereoisomeric yohimbine alkaloids using bioavailable monoterpene secolaganin as the te...

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Bibliographic Details
Main Authors: Meiyi Tang, Haigen Lu, Liansuo Zu
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-45140-2