Gastrodin Improves Cognitive Dysfunction in REM Sleep-Deprived Rats by Regulating TLR4/NF-κB and Wnt/β-Catenin Signaling Pathways

Gastrodin Improves Cognitive Dysfunction in REM Sleep-Deprived Rats by Regulating TLR4/NF-κB and Wnt/β-Catenin Signaling Pathways

Gastrodin is the active ingredient in <i>Gastrodia elata.</i> Our previous studies demonstrated that gastrodin ameliorated cerebral ischemia–reperfusion and hypoperfusion injury and improved cognitive deficit in Alzheimer’s disease. This study aims to examine the effects of gastrodin on...

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Bibliographic Details
Main Authors: Bo Liu, Fei Li, Yunyan Xu, Qin Wu, Jingshan Shi
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Brain Sciences
Subjects:
Gastrodin (GAS)
cognitive dysfunction
REM sleep-deprived rats
TLR4/NF-κB signaling pathways
Wnt/β-catenin signaling pathways
Online Access:https://www.mdpi.com/2076-3425/13/2/179

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https://www.mdpi.com/2076-3425/13/2/179

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