Spatial Lipidomics Reveals Anticancer Mechanisms of Bufalin in Combination with Cinobufagin in Tumor-Bearing Mice

Spatial Lipidomics Reveals Anticancer Mechanisms of Bufalin in Combination with Cinobufagin in Tumor-Bearing Mice

Bufalin (BFL) and cinobufagin (CBF) are the principal bioactive constituents of Chansu, a widely used traditional Chinese medicine (TCM). The synergistic effects of potential active components are responsible for the bioactivities of TCM. Our results showed that the cotreatment with BFL and CBF conf...

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Bibliographic Details
Main Authors: Jinghui Zhang, Yanjun Hong, Peisi Xie, Yang Chen, Lilong Jiang, Zhiyi Yang, Guodong Cao, Zhongjian Chen, Xuesong Liu, Yong Chen, Yongjiang Wu, Zongwei Cai
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
chansu
bufalin
cinobufagin
lipidomics
mass spectrometry imaging
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.593815/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.593815/full

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