The crucial role of particle surface reactivity in respirable quartz-induced reactive oxygen/nitrogen species formation and APE/Ref-1 induction in rat lung

<p>Abstract</p> <p>Persistent inflammation and associated excessive oxidative stress have been crucially implicated in quartz-induced pulmonary diseases, including fibrosis and cancer. We have investigated the significance of the particle surface reactivity of respirable quartz dus...

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Bibliographic Details
Main Authors: Haberzettl Petra, Höhr Doris, Becker Andrea, Knaapen Ad M, Albrecht Catrin, van Schooten Frederik J, Borm Paul JA, Schins Roel PF
Format: Article
Language:English
Published: BMC 2005-11-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/6/1/129