Repurposing Avasimibe to Inhibit Bacterial Glycosyltransferases

We are interested in identifying and characterizing small molecule inhibitors of bacterial virulence factors for their potential use as anti-virulence inhibitors. We identified from high-throughput screening assays a potential activity for avasimibe, a previously characterized acyl-coenzyme A: chole...

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Bibliographic Details
Main Authors: Md Kamrul Hasan, Samir El Qaidi, Peter McDonald, Anuradha Roy, Philip R. Hardwidge
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/11/3/370