Effects of compound-326, a selective delta-5 desaturase inhibitor, in ApoE knockout mice with two different protocols for atherosclerosis development

Purpose: We previously confirmed its anti-atherosclerotic effects by pre-treatment with compound-326, a selective delta-5 desaturase (D5D) inhibitor, in Western diet-fed ApoE knockout mice. In the present study, we evaluated effects of compound-326 in ApoE knockout mice with two different protocols...

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Bibliographic Details
Main Authors: Hiroki Nagase, Shuichi Takagahara, Yoshinori Satomi, Ayumi Ando, Kazuki Kubo, Shota Ikeda
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/31389