Effects of compound-326, a selective delta-5 desaturase inhibitor, in ApoE knockout mice with two different protocols for atherosclerosis development
Purpose: We previously confirmed its anti-atherosclerotic effects by pre-treatment with compound-326, a selective delta-5 desaturase (D5D) inhibitor, in Western diet-fed ApoE knockout mice. In the present study, we evaluated effects of compound-326 in ApoE knockout mice with two different protocols...
Main Authors: | Hiroki Nagase, Shuichi Takagahara, Yoshinori Satomi, Ayumi Ando, Kazuki Kubo, Shota Ikeda |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-02-01
|
Series: | Journal of Pharmacy & Pharmaceutical Sciences |
Online Access: | https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/31389 |
Similar Items
-
A Novel Selective Inhibitor of Delta-5 Desaturase Lowers Insulin Resistance and Reduces Body Weight in Diet-Induced Obese C57BL/6J Mice.
by: Hiroaki Yashiro, et al.
Published: (2016-01-01) -
Lack of alpha CGRP exacerbates the development of atherosclerosis in ApoE-knockout mice
by: Narumi Hashikawa-Hobara, et al.
Published: (2024-08-01) -
Fads2 knockout mice reveal that ALA prevention of hepatic steatosis is dependent on delta-6 desaturase activity
by: Blair MacLeod, et al.
Published: (2024-10-01) -
Voluntary exercise decreases atherosclerosis in nephrectomised ApoE knockout mice.
by: Cecilia M Shing, et al.
Published: (2015-01-01) -
Plasma Proteomic Changes of Atherosclerosis after Exercise in ApoE Knockout Mice
by: Chen-Chung Liao, et al.
Published: (2022-02-01)