Regulation of HCN Channels by Protein Interactions

Regulation of HCN Channels by Protein Interactions

Hyperpolarization-activated, cyclic nucleotide-sensitive (HCN) channels are key regulators of subthreshold membrane potentials in excitable cells. The four mammalian HCN channel isoforms, HCN1-HCN4, are expressed throughout the body, where they contribute to diverse physiological processes including...

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Bibliographic Details
Main Authors: Colin H. Peters, Rohit K. Singh, John R. Bankston, Catherine Proenza
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Physiology
Subjects:
HCN channels
accessory proteins
protein subunits
TRIP8b
IRAG
KCNE
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.928507/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2022.928507/full

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