An Engineered Synthetic Pathway for Discovering Nonnatural Nonribosomal Peptides in <italic toggle="yes">Escherichia coli</italic>
ABSTRACT Peptides that are synthesized independently of the ribosome in plants, fungi, and bacteria can have clinically relevant anticancer, antihemochromatosis, and antiviral activities, among many other. Despite their natural origin, discovering new natural products is challenging, and there is a...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2017-11-01
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Series: | mBio |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/mBio.01474-17 |