A drug delivery system constructed by a fusion peptide capturing exosomes targets to titanium implants accurately resulting the enhancement of osseointegration peri-implant

A drug delivery system constructed by a fusion peptide capturing exosomes targets to titanium implants accurately resulting the enhancement of osseointegration peri-implant

Abstract Background Exosomes derived from bone marrow mesenchymal stem cells (BMSC-exos) have been shown triggering osteogenic differentiation and mineralization of MSCs, but exosomes administered via bolus injections are rapidly sequestered and cleared. Therefore, we considered the implant as a new...

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Bibliographic Details
Main Authors: Xuewen Li, Zihao Liu, Shendan Xu, Xinying Ma, Zhezhe Zhao, Han Hu, Jiayin Deng, Cheng Peng, Yonglan Wang, Shiqing Ma
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2022-12-01
Series:Biomaterials Research
Subjects:
Titanium implants
Osseointegration
Exosomes
Drug delivery system
Online Access:https://doi.org/10.1186/s40824-022-00331-0

Internet

https://doi.org/10.1186/s40824-022-00331-0

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