Intravenous immunoglobulin and intravenous methylprednisolone as optimal induction treatment in chronic inflammatory demyelinating polyradiculoneuropathy: protocol of an international, randomised, double-blind, placebo-controlled trial (OPTIC)

Intravenous immunoglobulin and intravenous methylprednisolone as optimal induction treatment in chronic inflammatory demyelinating polyradiculoneuropathy: protocol of an international, randomised, double-blind, placebo-controlled trial (OPTIC)

Abstract Background International guidelines recommend either intravenous immunoglobulin (IVIg) or corticosteroids as first-line treatment for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). IVIg treatment usually leads to rapid improvement and is generally safe, but does not seem...

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Bibliographic Details
Main Authors: S. R. M. Bus, L. Zambreanu, A. Abbas, Y. A. Rajabally, R. D. M. Hadden, R. J. de Haan, C. A. J. M. de Borgie, M. P. Lunn, I. N. van Schaik, F. Eftimov, on behalf of the OPTIC study group
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Trials
Subjects:
Chronic inflammatory demyelinating polyradiculoneuropathy
CIDP
Randomised controlled trial
RCT
Corticosteroids
Methylprednisolone
Online Access:https://doi.org/10.1186/s13063-021-05083-1

Internet

https://doi.org/10.1186/s13063-021-05083-1

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