WEE1 and PARP-1 play critical roles in myelodysplastic syndrome and acute myeloid leukemia treatment

Abstract Background Myelodysplastic syndrome (MDS) is a clonal bone marrow disorder defined by cytopenia and is associated with an increased risk of transformation to acute myeloid leukemia (AML). The outcome of MDS is poor, so alternative therapeutic approaches are needed to improve survival. The i...

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Bibliographic Details
Main Authors: Seiichi Okabe, Yuko Tanaka, Mitsuru Moriyama, Akihiko Gotoh
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-023-02961-3