Platelet-derived growth factor (PDGF) signaling directs cardiomyocyte movement toward the midline during heart tube assembly

Platelet-derived growth factor (PDGF) signaling directs cardiomyocyte movement toward the midline during heart tube assembly

Communication between neighboring tissues plays a central role in guiding organ morphogenesis. During heart tube assembly, interactions with the adjacent endoderm control the medial movement of cardiomyocytes, a process referred to as cardiac fusion. However, the molecular underpinnings of this endo...

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Bibliographic Details
Main Authors: Joshua Bloomekatz, Reena Singh, Owen WJ Prall, Ariel C Dunn, Megan Vaughan, Chin-San Loo, Richard P Harvey, Deborah Yelon
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-01-01
Series:eLife
Subjects:
cardiac morphogenesis
myocardium
endoderm
Pdgfra
cardiac fusion
cardia bifida
Online Access:https://elifesciences.org/articles/21172

Internet

https://elifesciences.org/articles/21172

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