Rosiglitazone induces hepatocyte injury by increasing DCA accumulation through OATP1A4 inhibiting in mice

Rosiglitazone induces hepatocyte injury by increasing DCA accumulation through OATP1A4 inhibiting in mice

Rosiglitazone (RL), a second-generation thiazolidinedione (TZD), is an oral antidiabetic agent that is reportedly associated with hepatotoxicity. However, the molecular mechanism of Rosiglitazone induced hepatotoxicity has not been reported yet. To minimize clinical risk, in the present study, toxic...

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Bibliographic Details
Main Authors: Daopeng Tan, Lei Ling, Lin Qin, Yanliu Lu, Di Wu, Yuqi He
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Arabian Journal of Chemistry
Subjects:
Rosiglitazone
Drug-induced liver injury
Hepatotoxicity
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Online Access:http://www.sciencedirect.com/science/article/pii/S1878535223006044

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http://www.sciencedirect.com/science/article/pii/S1878535223006044

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