TP53 Gene 72 Arg/Pro (rs1042522) single nucleotide polymorphism increases the risk and the severity of chronic lymphocytic leukemia

TP53 Gene 72 Arg/Pro (rs1042522) single nucleotide polymorphism increases the risk and the severity of chronic lymphocytic leukemia

BackgroundGenetic variations in TP53 gene are known to be important in chronic lymphocytic leukemia (CLL) and may cause its inactivation which is associated with an aggressive form of the disease. Single nucleotide polymorphism (rs1042522:G>C) in TP53 gene at codon 72 encodes for arginine (Ar...

Full description

Bibliographic Details
Main Authors: Asma Ounalli, Imen Moumni, Amal Mechaal, Aya Chakroun, Mbarka Barmat, Rim El Elj Rhim, Samia Menif, Ines Safra
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Oncology
Subjects:
chronic lymphocytic leukemia
TP53 gene
polymorphism 72
hematological parameters
clinical biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1272876/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1272876/full

Similar Items