Changes in nano-mechanical properties of human epidermal cornified cells in children with atopic dermatitis [version 2; peer review: 2 approved]

Background: Impaired skin barrier is an important etiological factor in atopic dermatitis (AD). The structural protein filaggrin (FLG) plays a major role in maintenance of the competent skin barrier and its deficiency is associated with enhanced susceptibility to mechanical injury. Here we examined...

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Bibliographic Details
Main Authors: Marek Haftek, Maeve A McAleer, Ivone Jakasa, WH Irwin McLean, Sanja Kezic, Alan D. Irvine
Format: Article
Language:English
Published: Wellcome 2020-07-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/5-97/v2