PD-1/PD-L1 in Cancer: Pathophysiological, Diagnostic and Therapeutic Aspects

PD-1/PD-L1 in Cancer: Pathophysiological, Diagnostic and Therapeutic Aspects

Immune evasion is a key strategy adopted by tumor cells to escape the immune system while promoting their survival and metastatic spreading. Indeed, several mechanisms have been developed by tumors to inhibit immune responses. PD-1 is a cell surface inhibitory receptor, which plays a major physiolog...

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Bibliographic Details
Main Authors: Enrico Munari, Francesca R. Mariotti, Linda Quatrini, Pietro Bertoglio, Nicola Tumino, Paola Vacca, Albino Eccher, Francesco Ciompi, Matteo Brunelli, Guido Martignoni, Giuseppe Bogina, Lorenzo Moretta
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
NK cells
PD-1
PD-L1
glucocorticoids
immunotherapy
cancer
Online Access:https://www.mdpi.com/1422-0067/22/10/5123

Internet

https://www.mdpi.com/1422-0067/22/10/5123

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