Detection of Prions in Brain Homogenates and CSF Samples Using a Second-Generation RT-QuIC Assay: A Useful Tool for Retrospective Analysis of Archived Samples

The possibilities for diagnosing prion diseases have shifted significantly over the last 10 years. The RT-QuIC assay option has been added for neuropsychiatric symptoms, supporting biomarkers and final <i>post-mortem</i> confirmation. Samples of brain homogenates used for final diagnosis...

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Bibliographic Details
Main Authors: Tibor Moško, Soňa Galušková, Radoslav Matěj, Magdalena Brůžová, Karel Holada
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/10/6/750