Hydrogen Sulfide Regulates SERCA2a Ubiquitylation via Muscle RING Finger-1 S-Sulfhydration to Affect Cardiac Contractility in db/db Mice

Hydrogen Sulfide Regulates SERCA2a Ubiquitylation via Muscle RING Finger-1 S-Sulfhydration to Affect Cardiac Contractility in db/db Mice

Hydrogen sulfide (H<sub>2</sub>S), as a gasotransmitter, is involved in various pathophysiological processes. Diabetic cardiomyopathy (DCM) is a major complication of diabetes mellitus (DM), which leads to structural and functional abnormalities of the myocardium and eventually causes he...

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Bibliographic Details
Main Authors: Shuo Peng, Dechao Zhao, Qianzhu Li, Mengyi Wang, Shiwu Zhang, Kemiao Pang, Jiayi Huang, Fanghao Lu, He Chen, Weihua Zhang
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cells
Subjects:
hydrogen sulfide
diabetic cardiomyopathy
SERCA2a
MuRFl
S-sulfhydration
Online Access:https://www.mdpi.com/2073-4409/11/21/3465

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https://www.mdpi.com/2073-4409/11/21/3465

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