Translational initiation in E. coli occurs at the correct sites genome-wide in the absence of mRNA-rRNA base-pairing

Shine-Dalgarno (SD) motifs are thought to play an important role in translational initiation in bacteria. Paradoxically, ribosome profiling studies in E. coli show no correlation between the strength of an mRNA’s SD motif and how efficiently it is translated. Performing profiling on ribosomes with a...

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Bibliographic Details
Main Authors: Kazuki Saito, Rachel Green, Allen R Buskirk
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/55002