Total and High Molecular Weight Adiponectin Expression Is Decreased in Patients with Common Variable Immunodeficiency: Correlation with Ig Replacement Therapy

Total and High Molecular Weight Adiponectin Expression Is Decreased in Patients with Common Variable Immunodeficiency: Correlation with Ig Replacement Therapy

Adiponectin (Acrp30) is an adipokine widely studied for its beneficial metabolic properties. It circulates as low molecular weight (LMW), medium molecular weight (MMW), and high molecular weight (HMW) oligomers. The latter exerts the most potent biological effects. Acrp30 attracted renewed interest...

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Bibliographic Details
Main Authors: Antonio Pecoraro, Ersilia Nigro, Rita Polito, Maria Ludovica Monaco, Olga Scudiero, Ilaria Mormile, Azzurra Cesoni Marcelli, Mario Capasso, Francesco Habetswallner, Arturo Genovese, Aurora Daniele, Giuseppe Spadaro
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Immunology
Subjects:
common variable immunodeficiency
adiponectin
high molecular weight oligomers
immunoglobulin
adipose tissue
intravenous immunoglobulin
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00895/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00895/full

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