Intranasal administration with recombinant vaccine PRVXJ-delgE/gI/TK-S induces strong intestinal mucosal immune responses against PDCoV

Intranasal administration with recombinant vaccine PRVXJ-delgE/gI/TK-S induces strong intestinal mucosal immune responses against PDCoV

Abstract Porcine deltacoronavirus (PDCoV) is a novel coronavirus that causes enteric diseases in pigs leading to substantial financial losses within the industry. The absence of commercial vaccines and limited research on PDCoV vaccines presents significant challenges. Therefore, we evaluated the sa...

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Bibliographic Details
Main Authors: Bingzhou Huang, Yao Huang, Lishuang Deng, Tong Xu, Zhijie Jian, Siyuan Lai, Yanru Ai, Ling Zhu, Zhiwen Xu
Format: Article
Language:English
Published: BMC 2023-09-01
Series:BMC Veterinary Research
Subjects:
PRV
PDCoV
Spike protein
Recombinant vaccine
Intestinal mucosal immunity
Online Access:https://doi.org/10.1186/s12917-023-03739-5

Internet

https://doi.org/10.1186/s12917-023-03739-5

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