HSPiP and QbD oriented optimized stearylamine-elastic liposomes for topical delivery of ketoconazole to treat deep seated fungal infections: In vitro and ex vivo evaluations

HSPiP and QbD oriented optimized stearylamine-elastic liposomes for topical delivery of ketoconazole to treat deep seated fungal infections: In vitro and ex vivo evaluations

The study explored stearylamine containing cationic elastic liposomes to improve topical delivery and efficacy of ketoconazole (KETO) to treat deeply seated fungal infections. Stearylamine was used for dual functionalities (electrostatic interaction and flexibility in lipid bilayer). Hansen solubili...

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Bibliographic Details
Main Authors: Afzal Hussain, Mohammad A. Altamimi, Yaser Saleh Alneef
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:International Journal of Pharmaceutics: X
Subjects:
Ketoconazole
HSPiP
Stearylamine
Cationic OKEL1
In-vitro-ex-vivo studies
Online Access:http://www.sciencedirect.com/science/article/pii/S2590156724000513

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http://www.sciencedirect.com/science/article/pii/S2590156724000513

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