Investigation of phytochemicals isolated from selected Saudi medicinal plants as natural inhibitors of SARS CoV-2 main protease: In vitro, molecular docking and simulation analysis

Investigation of phytochemicals isolated from selected Saudi medicinal plants as natural inhibitors of SARS CoV-2 main protease: In vitro, molecular docking and simulation analysis

The escalation of many coronavirus variants accompanied by the lack of an effective cure has motivated the hunt for effective antiviral medicines. In this regard, 18 Saudi Arabian medicinal plants were evaluated for SARS CoV-2 main protease (Mpro) inhibition activity. Among them, Terminalia brownii...

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Bibliographic Details
Main Authors: Yousef T.M. Alharbi, Wael M. Abdel-Mageed, Omer A. Basudan, Ramzi A. Mothana, Md Tabish Rehman, Ali A. ElGamal, Ali S. Alqahtani, Omer I. Fantoukh, Mohamed F. AlAjmi
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Saudi Pharmaceutical Journal
Subjects:
SARS-CoV-2 Mpro
Saudi plants
Terminalia brownii
Acacia asak
Hydrolysable tannins
Flavonoid C-glycosides
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016424000732

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http://www.sciencedirect.com/science/article/pii/S1319016424000732

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