Targeted delivery of irinotecan to colon cancer cells using epidermal growth factor receptor-conjugated liposomes

Targeted delivery of irinotecan to colon cancer cells using epidermal growth factor receptor-conjugated liposomes

Abstract Background CPT-11 (irinotecan) is one of the most efficient agents used for colorectal cancer chemotherapy. However, as for many other chemotherapeutic drugs, how to minimize the side effects of CPT-11 still needs to be thoroughly described. Objectives This study aimed to develop the CPT-11...

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Bibliographic Details
Main Authors: Yongwei Liu, Xinghui Li, Renqun Pen, Wei Zuo, Ya Chen, Xiuying Sun, Juhua Gou, Qianwen Guo, Maoling Wen, Wuqi Li, Shuangjiang Yu, Hao Liu, Min Huang
Format: Article
Language:English
Published: BMC 2022-08-01
Series:BioMedical Engineering OnLine
Subjects:
Irinotecan (CPT-11)
DSPE-PEG2000
EGFR
Colorectal cancer
SW620 cell
Online Access:https://doi.org/10.1186/s12938-022-01012-8

Internet

https://doi.org/10.1186/s12938-022-01012-8

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