Cryo-Structuring of Polymeric Systems. Poly(Vinyl Alcohol)-Based Cryogels Loaded with the Poly(3-hydroxybutyrate) Microbeads and the Evaluation of Such Composites as the Delivery Vehicles for Simvastatin

Cryo-Structuring of Polymeric Systems. Poly(Vinyl Alcohol)-Based Cryogels Loaded with the Poly(3-hydroxybutyrate) Microbeads and the Evaluation of Such Composites as the Delivery Vehicles for Simvastatin

Highly porous composite poly(vinyl alcohol) (PVA) cryogels loaded with the poly(3-hydroxybutyrate) (PHB) microbeads containing the drug, simvastatin (SVN), were prepared via cryogenic processing (freezing—storing frozen—defrosting) of the beads’ suspensions in aqueous PVA solution. The rigidity of t...

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Bibliographic Details
Main Authors: Dmitrii A. Michurov, Tatiana K. Makhina, Valentina Siracusa, Anton P. Bonartsev, Vladimir I. Lozinsky, Alexey L. Iordanskii
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Polymers
Subjects:
poly(vinyl alcohol)
poly(3-hydroxybutyrate)
simvastatin
composite cryogels
physico-mechanical properties
microstructure
Online Access:https://www.mdpi.com/2073-4360/14/11/2196

Internet

https://www.mdpi.com/2073-4360/14/11/2196

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