Detection of tuberculosis drug resistance: a comparison by Mycobacterium tuberculosis MLPA assay versus Genotype®MTBDRplus

Detection of tuberculosis drug resistance: a comparison by Mycobacterium tuberculosis MLPA assay versus Genotype®MTBDRplus

BACKGROUND To cope with the emergence of multidrug-resistant tuberculosis (MDR-TB), new molecular methods that can routinely be used to screen for a wide range of drug resistance related genetic markers in the Mycobacterium tuberculosis genome are urgently needed. OBJECTIVE To evaluate the perfor...

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Bibliographic Details
Main Authors: Paula Fernanda Gonçalves dos Santos, Elis Regina Dalla Costa, Daniela M Ramalho, Maria Lucia Rossetti, Regina Bones Barcellos, Luciana de Souza Nunes, Leonardo Souza Esteves, Rodrigo Rodenbusch, Richard M Anthony, Indra Bergval, Sarah Sengstake, Miguel Viveiros, Afrânio Kritski, Martha M Oliveira
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ)
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
tuberculosis
MLPA
GenoTypeMTBDR®plus
isoniazid resistance
rifampicin resistance
multidrug resistance
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762017000600396&lng=en&tlng=en

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