AIV polyantigen epitope expressed by recombinant baculovirus induces a systemic immune response in chicken and mouse models

Abstract Background The protective efficacy of avian influenza virus (AIV) vaccines is unsatisfactory due to the presence of various serotypes generated by genetic reassortment. Thus, immunization with a polyantigen chimeric epitope vaccine may be an effective strategy for protecting poultry from in...

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Bibliographic Details
Main Authors: Lei Yu, Jun Pan, Guangli Cao, Mengsheng Jiang, Yunshan Zhang, Min Zhu, Zi Liang, Xing Zhang, Xiaolong Hu, Renyu Xue, Chengliang Gong
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Virology Journal
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12985-020-01388-w