A branching model of lineage differentiation underpinning the neurogenic potential of enteric glia

Abstract Glial cells have been proposed as a source of neural progenitors, but the mechanisms underpinning the neurogenic potential of adult glia are not known. Using single cell transcriptomic profiling, we show that enteric glial cells represent a cell state attained by autonomic neural crest cell...

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Bibliographic Details
Main Authors: Anna Laddach, Song Hui Chng, Reena Lasrado, Fränze Progatzky, Michael Shapiro, Alek Erickson, Marisol Sampedro Castaneda, Artem V. Artemov, Ana Carina Bon-Frauches, Eleni-Maria Amaniti, Jens Kleinjung, Stefan Boeing, Sila Ultanir, Igor Adameyko, Vassilis Pachnis
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-41492-3