N-Alkyl derivatives of diosgenyl 2-amino-2-deoxy-β-D-glucopyranoside; synthesis and antimicrobial activity

N-Alkyl derivatives of diosgenyl 2-amino-2-deoxy-β-D-glucopyranoside; synthesis and antimicrobial activity

Diosgenyl 2-amino-2-deoxy-β-D-glucopyranoside is a synthetic saponin exhibiting attractive pharmacological properties. Different pathways tested by us to obtain this glycoside are summarized here. Moreover, the synthesis of N-alkyl and N,N-dialkyl derivatives of the glucopyranoside is presented. Eva...

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Bibliographic Details
Main Authors: Agata Walczewska, Daria Grzywacz, Dorota Bednarczyk, Małgorzata Dawgul, Andrzej Nowacki, Wojciech Kamysz, Beata Liberek, Henryk Myszka
Format: Article
Language:English
Published: Beilstein-Institut 2015-05-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
antimicrobial activities
D-glucosamine
diosgenin glycosylation
N-alkylation
Online Access:https://doi.org/10.3762/bjoc.11.97

Internet

https://doi.org/10.3762/bjoc.11.97

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