Role of genetic variations of chitinase 3-like 1 in bronchial asthmatic patients

Abstract Background Single nucleotide polymorphisms (SNPs) in chitinase 3-like 1 (CHI3L1) are associated with bronchial severity and pulmonary function. CHI3L1 proteins are involved in both innate and adaptive immune responses; however, to date, the correlation of these SNPs and their age of onset o...

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Bibliographic Details
Main Authors: Kazuyuki Abe, Yutaka Nakamura, Kohei Yamauchi, Makoto Maemondo
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Clinical and Molecular Allergy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12948-018-0086-7