DNA methylation presents distinct binding sites for human transcription factors

DNA methylation presents distinct binding sites for human transcription factors

DNA methylation, especially CpG methylation at promoter regions, has been generally considered as a potent epigenetic modification that prohibits transcription factor (TF) recruitment, resulting in transcription suppression. Here, we used a protein microarray-based approach to systematically survey...

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Bibliographic Details
Main Authors: Shaohui Hu, Jun Wan, Yijing Su, Qifeng Song, Yaxue Zeng, Ha Nam Nguyen, Jaehoon Shin, Eric Cox, Hee Sool Rho, Crystal Woodard, Shuli Xia, Shuang Liu, Huibin Lyu, Guo-Li Ming, Herschel Wade, Hongjun Song, Jiang Qian, Heng Zhu
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2013-09-01
Series:eLife
Subjects:
DNA methylation
protein-DNA interaction
protein microarray
transcription factor
epigenetic
transcription regulation
Online Access:https://elifesciences.org/articles/00726

Internet

https://elifesciences.org/articles/00726

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