Genetic and environmental factors of atopy

Atopy is a common immune disorder characterized by raised IgE levels, which lead to clinical disorders (i.e. primarily bronchial asthma, atopic dermatitis and allergic rhinoconjuctivitis). Interleukin (IL)-4 and IL-13, derived from T-helper cell type 2 (Th2) subsets, are central in mediating IgE pro...

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Bibliographic Details
Main Authors: Akiko Otsu, Taro Shirakawa
Format: Article
Language:English
Published: Elsevier 2002-01-01
Series:Allergology International
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015313356