Spontaneous Activity of CB2 Receptors Attenuates Stress-Induced Behavioral and Neuroplastic Deficits in Male Mice

Spontaneous Activity of CB2 Receptors Attenuates Stress-Induced Behavioral and Neuroplastic Deficits in Male Mice

The monoaminergic theory of depression/anxiety disorders cannot fully explain the behavioral and neuroplastic changes observed after ADs chronic treatment. Endocannabinoid system, which comprises CB2 receptors, has been associated with the chronic effects of these drugs, especially in stressed mice....

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Bibliographic Details
Main Authors: Melissa A. Ribeiro, Rafael P. Aguiar, Franciele F. Scarante, Eduardo J. Fusse, Rubia M. W. de Oliveira, Francisco S. Guimaraes, Alline C Campos
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Pharmacology
Subjects:
chronic stress
CB2 inverse agonist
escitalopram
hippocampus
neuroplasticity
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.805758/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.805758/full

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