Distinct transcriptional roles for Histone H3-K56 acetylation during the cell cycle in Yeast
H3K56Ac promotes nucleosome turnover at promoter-proximal locations and assembly of new nucleosomes during S phase. Here the authors find that H3K56Ac is both a genome-wide activator of transcription in yeast while also repressing promiscuous transcription that occurs after replication fork passage.
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2019-09-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-019-12400-5 |