Heterogeneous Distribution of Genetic Mutations in Myosin Binding Protein-C Paralogs

Heterogeneous Distribution of Genetic Mutations in Myosin Binding Protein-C Paralogs

Myosin binding protein-C (MyBP-C) is a sarcomeric protein which regulates the force of contraction in striated muscles. Mutations in the MYBPC family of genes, including slow skeletal (MYBPC1), fast skeletal (MYBPC2) and cardiac (MYBPC3), can result in cardiac and skeletal myopathies. Nonetheless, t...

Full description

Bibliographic Details
Main Authors: Darshini A. Desai, Vinay J. Rao, Anil G. Jegga, Perundurai S. Dhandapany, Sakthivel Sadayappan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Genetics
Subjects:
MYBPC1
MYBPC2
MYBPC3
hypertrophic cardiomyopathy
distal arthrogryposis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.896117/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.896117/full

Similar Items