Interplay between proteasome inhibitors and NF-κB pathway in leukemia and lymphoma: a comprehensive review on challenges ahead of proteasome inhibitors

Abstract The current scientific literature has extensively explored the potential role of proteasome inhibitors (PIs) in the NF-κB pathway of leukemia and lymphoma. The ubiquitin-proteasome system (UPS) is a critical component in regulating protein degradation in eukaryotic cells. PIs, such as BTZ,...

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Bibliographic Details
Main Authors: Mahdi Pakjoo, Seyed Esmaeil Ahmadi, Mohammad Zahedi, Niloofar Jaafari, Reyhane Khademi, Ali Amini, Majid Safa
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Cell Communication and Signaling
Subjects:
Online Access:https://doi.org/10.1186/s12964-023-01433-5