Unravelling the Impact of the Genetic Variant rs1042058 within the TPL2 Risk Gene Locus on Molecular and Clinical Disease Course Patients with Inflammatory Bowel Disease

Unravelling the Impact of the Genetic Variant rs1042058 within the TPL2 Risk Gene Locus on Molecular and Clinical Disease Course Patients with Inflammatory Bowel Disease

<b>Background:</b> The single nucleotide polymorphism (SNP) rs1042058 within the gene locus encoding tumor progression locus 2 (TPL2) has been recently identified as a risk gene for inflammatory bowel disease (IBD). TPL2 has been shown to regulate pro-inflammatory signaling and cytokine...

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Bibliographic Details
Main Authors: Yasser Morsy, Nathalie Brillant, Yannick Franc, Michael Scharl, Marcin Wawrzyniak, on behalf of the Swiss IBD Cohort Study Group
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
TPL2
IBD
ulcerative colitis
Crohn’s disease
Online Access:https://www.mdpi.com/2073-4409/10/12/3589

Internet

https://www.mdpi.com/2073-4409/10/12/3589

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