From DNA Copy Number Gains and Tumor Dependencies to Novel Therapeutic Targets for High-Risk Neuroblastoma

From DNA Copy Number Gains and Tumor Dependencies to Novel Therapeutic Targets for High-Risk Neuroblastoma

Neuroblastoma is a pediatric tumor arising from the sympatho-adrenal lineage and a worldwide leading cause of childhood cancer-related deaths. About half of high-risk patients die from the disease while survivors suffer from multiple therapy-related side-effects. While neuroblastomas present with a...

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Bibliographic Details
Main Authors: Bieke Decaesteker, Kaat Durinck, Nadine Van Roy, Bram De Wilde, Christophe Van Neste, Stéphane Van Haver, Stephen Roberts, Katleen De Preter, Vanessa Vermeirssen, Frank Speleman
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Journal of Personalized Medicine
Subjects:
neuroblastoma
DNA copy number gains
<i>MYCN</i>
dependency
drug targets
Online Access:https://www.mdpi.com/2075-4426/11/12/1286

Internet

https://www.mdpi.com/2075-4426/11/12/1286

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