A quantitative deficiency in peripheral blood Vγ9Vδ2 cells is a negative prognostic biomarker in ovarian cancer patients.

A quantitative deficiency in peripheral blood Vγ9Vδ2 cells is a negative prognostic biomarker in ovarian cancer patients.

Vγ9Vδ2 cells are cytotoxic T cells that are able to recognize epithelial ovarian carcinoma (EOC) cells. Therefore, Vγ9Vδ2 cell-based adoptive transfer is an attractive therapy for EOC. However, the inefficient ex vivo expansion after specific stimulation of Vγ9Vδ2 cells from some patients and the re...

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Bibliographic Details
Main Authors: Aurélie Thedrez, Vincent Lavoué, Benoit Dessarthe, Pascale Daniel, Sébastien Henno, Isabelle Jaffre, Jean Levêque, Véronique Catros, Florian Cabillic
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3662688?pdf=render

Internet

http://europepmc.org/articles/PMC3662688?pdf=render

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