Genomic rearrangement screening of the BRCA1 from seventy Iranian high-risk breast cancer families

Genomic rearrangement screening of the BRCA1 from seventy Iranian high-risk breast cancer families

Background: The second leading cause of cancer deaths in women is breast cancer. Germline mutations in susceptibility breast cancer gene BRCA1 increase the lifetime risk of breast cancer. Eighty-one large genomic rearrangements (LGRs) have been reported up to date in BRCA1 gene, and evaluation of th...

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Bibliographic Details
Main Authors: Maryam Sedghi, Elham Esfandiari, Esmat Fazel-Najafabadi, Mansoor Salehi, Abbas Salavaty, Shirin Fattahpour, Leila Dehghani, Nayerossadat Nouri, Fariborz Mokarian
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Journal of Research in Medical Sciences
Subjects:
BRCA1 gene
breast cancer
large genomic rearrangements
multiplex ligation-dependent probe amplification
Online Access:http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2016;volume=21;issue=1;spage=95;epage=95;aulast=Sedghi

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http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2016;volume=21;issue=1;spage=95;epage=95;aulast=Sedghi

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