Identification and functional characterization of a novel arginine/ornithine transporter, a member of a cationic amino acid transporter subfamily in the Trypanosoma cruzi genome

Abstract Background Trypanosoma cruzi, the etiological agent of Chagas disease, is auxotrophic for arginine. It obtains this amino acid from the host through transporters expressed on the plasma membrane and on the membranes of intracellular compartments. A few cationic amino acid transporters have...

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Bibliographic Details
Main Authors: Cristina Henriques, Megan P. Miller, Marcos Catanho, Técia Maria Ulisses de Carvalho, Marco Aurélio Krieger, Christian M. Probst, Wanderley de Souza, Wim Degrave, Susan Gaye Amara
Format: Article
Language:English
Published: BMC 2015-06-01
Series:Parasites & Vectors
Subjects:
Online Access:https://doi.org/10.1186/s13071-015-0950-y